An efficient synthesis of enantiopure (R)-heteroarylpyrimidine analogs.
نویسندگان
چکیده
An efficient synthesis of enantiopure (R)-heteroarylpyrimidine analogs is described here, which involves introduction of a chiral group, formation and separation of diasteroisomers and final transformation of an amide to an ester. The absolute configuration of the enantiopure HAPs is confirmed by X-ray analysis of their intermediates.
منابع مشابه
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ورودعنوان ژورنال:
- Molecules
دوره 18 9 شماره
صفحات -
تاریخ انتشار 2013